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Let us consider the more recent Standard formats: Zendikar-Scars of Mirrodin Standard (after the [card]Jace, the Mind Sculptor[/card] and [card]Stoneforge Mystic[/card] bannings): [deck title=U/R Twin by Anders Simpson Wolf] [Creatures] *4 Deceiver Exarch [/Creatures] [Spells] *4 Shrine of Piercing Vision *4 Splinter Twin *2 Dismember *4 Dispel *2 Into the Roil *2 Mana Leak *2 Mental Misstep *1 Twisted Image *4 Gitaxian Probe *4 Ponder *4 Preordain [/Spells] [Lands] *8 Island *5 Mountain *2 Arid Mesa *2 Halimar Depths *2 Misty Rainforest *4 Scalding Tarn [/Lands] [Sideboard] *2 Spellskite *2 Azure Mage *3 Grim Lavamancer *1 Mental Misstep *2 Mutagenic Growth *2 Negate *1 Shatter *2 Pyroclasm [/Sideboard] [/deck] This is the last time that Standard saw a viable two-card combo deck, and astute readers can see why

Honorable Mentions: Thraben Inspector Toolcraft Exemplar Martyr of Sands Shahrazad Lin Sivvi, Defiant Hero Empyrial Armor Councils Judgment Gideon, Ally of Zendikar Cataclysm Yosei, the Morning Star
If any cards have the keywords at the start of your turn, activate their abilities now
If you've already got seven mana to unlock this Room, you can probably already pay for the spells in your hand
The original Innistrad boxes sell for more than $800 by comparison, one of the most expensive non-Reserved List sets